Research
Research Interests
Adhesion, colonization and virulence properties of human oral micro-organisms, in particular Streptococcus, Candida, and Treponema. Mechanisms of biofilm formation, microbial community development and invasion of oral tissues.
Publications
2008
Jenkinson HF, Lamont RJ. 2007. The oral microbial ecosystem and beyond. In: Wang HH, Schlesinger LS, eds. Foodborne Microbes: Shaping the Host Ecosystem. Washington DC, ASM Press, in press.
2007
Kerrigan SW, Jakubovics NS, Keane C, Maguire P, Wynne K, Jenkinson HF, Cox D. 2007. The role of Streptococcus gordonii surface proteins SspA/B and Hsa in platelet function. Infection and Immunity 75: 5740-5747.
Bamford CV, Fenno JC, Jenkinson HF, Dymock D. 2007. The chymotrypsin-like protease (CTLP) complex of Treponema denticola ATCC 35405 mediates fibrinogen adherence and degradation. Infection and Immunity 75: 4364-4372.
Jonasson A, Eriksson C, Jenkinson HF, Kallestal C, Johansson I, Strömberg N. 2007. Innate immunity glycoprotein gp-340 varinats may modulate human susceptibility to dental caries. BMC Infectious Diseases 7: 57.
Barbour ME, O'Sullivan DJ, Jenkinson HF, Jagger DC. 2007. The effects of polishing methods on surface morphology, roughness and bacterial colonization of titanium abutments. Journal of Materials Science: Materials in Medicine 18: 1439-1447.
Eriksson C, Frängsmyr L, Danielsson-Niemi L, Loimaranta V, Holmskov U, Leffler H, Jenkinson HF, Strömberg N. 2007. Iso- and glyoforms of the scavenger receptor cysteine-rich protein gp-340 with differential bacterial aggregation activity. Glycoconjugate Journal 24: 131-42.
Nobbs AH, Shearer BH, Drobni M, Jepson MA, Jenkinson HF. 2007. Adherence and internalization of Streptococcus gordonii by epithelial cells involves β1 integrin recognition by SspA and SspB (antigen I/II family) polypeptides. Cellular Microbiology 9: 65-83.
2006
Lamont RJ, Jenkinson HF. 2006. Oral microbial ecology. In: Lamont RJ, Burne RA, Lantz MS, LeBlanc DJ, eds. Oral Microbiology. Washington DC, ASM Press, pp 89-105.
Jakubovics NS, Brittan JL, Kerrigan S, Cox D, Strömberg N, Jenkinson HF. 2006. Interactions of mitis group streptococci with sialic acid receptors. In: Sriprakash KS ed. Streptococci – New Insights into an Old Enemy, ICS 1289. Amsterdam, Elsevier, pp 275-278.
Finn A, Jenkinson HF. 2006. The pneumococcus: old man's friend and children's foe. Microbiology 152: 281-283.
Wescombe PA, Upton M, Dierksen KP, Ragland NL, Sivabalan S, Wirawan R, Inglis M, Moore CJ, Walker GV, Chilcott C, Jenkinson HF, Tagg JR. 2006. Production of lantibiotic salivaricin A and its variants by oral streptococci and the use of a specific induction assay to detect their presence in human saliva. Applied and Environmental Microbiology 72: 1459-1466.
Jenkinson HF, Vickerman MM. 2006. Genetics of sanguinis group streptococci. In: Fischetti VA, Novick RP, Ferretti JJ, Portnoy DA, Rood JI, eds. Gram-Positive Pathogens, 2nd Edition. Washington DC, ASM Press, pp 347-355.
2005
Jenkinson HF, Lamont RJ. 2005. Oral microbial communities in sickness and in health. Trends in Microbiology 13: 589-595.
Jakubovics NS, Kerrigan SW, Nobbs AH, Strömberg N, van Dolleweerd CJ, Cox DM, Kelly CG, Jenkinson HF. 2005. Functions of cell surface anchored antigen I/II family and Hsa polypeptides in interactions of Streptococcus gordonii with host receptors. Infection and Immunity 73: 6629-6638.
Edwards AM, Woodward MJ, Jenkinson HF, Dymock D. 2005. Binding properties and interactive domains of the major surface protein (Msp) adhesin of Treponema denticola ATCC 35405. Infection and Immunity 73: 2891-2898.
Pracht D, Elm C, Gerber J, Bergmann S, Rohde M, Seiler M, Kim KS, Jenkinson HF, Nau R, Hammerschmidt S. 2005. PavA of Streptococcus pneumoniae modulates adherence, invasion and meningeal inflammation. Infection and Immunity 73: 2680-2689.
Jakubovics NS, Strömberg N, van Dolleweerd CJ, Kelly CG, Jenkinson HF. 2005. Differential binding specificities of oral streptococcal antigen I/II family adhesins for human or bacterial ligands. Molecular Microbiology 55: 1591-1605.
Loimaranta V, Jakubovics NS, Hytönen J, Finne J, Jenkinson HF, Strömberg N. 2005. Fluid or surface phase human salivary scavenger protein gp340 expose different bacterial recognition properties. Infection and Immunity 73: 2245-2252.
Walter J, Chagnaud P, Tannock GW, Loach DM, Bello FD, Jenkinson HF, Hammes WP, Hertel C. 2005. A high molecular mass surface protein (Lsp) and methionine sulfoxide reductase B (MsrB) contribute to the ecological performance of Lactobacillus reuteri in the gut of mice. Applied and Environmental Microbiology 71: 979-986.